Grant Projects & Impact 2024-2025

Grant Projects & Impact 2024-2025

Mission and Vision

The MUHC Foundation is committed to supporting excellence in patient care, research, and world-class teaching at the McGill University Health Centre (including the MUHC-RI), Québec's leading research hospital and one of the largest bilingual academic health networks in North America.

The MUHC is a vital institution for Quebecers, serving a population of 1.9 million people across 63% of the province's territory. Each year, the MUHC welcomes more than 515,000 outpatient visits — including 177,000 emergency visits — and performs over 30,000 surgeries. As a leading referral centre for highly specialized care in oncology, cardiology, surgery, transplantation, and rare diseases, the MUHC is where some of the most complex and critical cases in Québec are treated. It is also where some of Canada's most important medical discoveries are made.

At the heart of this research mission is the Research Institute of the MUHC (RI-MUHC) — ranked first in Québec and one of the top three hospital-based research centres in Canada. The RI-MUHC brings together 744 fundamental, clinical, and evaluative researchers, supported by 1,490 research trainees and 1,476 support staff across 30,694 square metres of research space.. In 2024–2025, RI-MUHC researchers produced over 2,553 peer-reviewed scientific publications, 72% of which appeared in top quartile journals, and delivered over 2,500 scientific talks worldwide. The Institute maintains active research collaborations with 85 countries, and over the past five years has seen total research funding grow by 37%, including a 76% increase in clinical research funding alone.

The close integration of the MUHC's Glen site and the RI-MUHC means that discoveries move rapidly from the laboratory to the bedside, ensuring Quebecers are among the first to benefit from life-saving advancements.

The MUHC Foundation directs donor funding where it can have the greatest impact: innovative projects that push the boundaries of what is possible in medicine. Our strategic plan set a target of more than 80% of grants supporting innovative initiatives, defined as initiatives introducing new ideas, research, methods, technologies, products, or services aimed at improving health care delivery, patient care and outcomes, and overall efficiency within the health care system. In the last 3 year, we exceeded that goal, with 89% of grants directed toward innovation-focused programs in 2024/2025.

We focus on the most pressing health challenges of our time: eradicating cancer as a life-threatening disease, transforming cardiac care, combating antibiotic resistance, and training the next generation of health care leaders.

Our funding supports a wide range of groundbreaking initiatives, including:

  • Cancer Research & Early Detection. Liquid biopsy is a minimally invasive screening test that detects tumor DNA in blood, urine, or saliva — catching cancer earlier and with less burden on patients. The DOvEEgene test is improving early detection of ovarian cancer and helping improve patient outcomes. Researchers are also growing tumors in labs to test treatments before they reach patients, and building a biobank of cancer tissues to deepen our understanding of different cancer types.
  • Cardiovascular Health. The Courtois Cardiovascular Signature Program is a landmark study mapping participants' blood, genomes, and biomes, while imaging their hearts and carotid arteries, all to understand how and why cardiovascular disease develops, with the ultimate goal of reducing heart disease across Canada.
  • Diabetes & Chronic Disease. The DECIDE-CV program is transforming how we screen for Type 2 Diabetes (T2DM), using AI-based technologies and wearable devices to identify and support individuals with T2DM, particularly those with cardiovascular risk factors.
  • Infectious Disease & Global Health. The Infectious Diseases and Immunity in Global Health Program (MI4) is at the forefront of the fight against microbial threats, antimicrobial resistance, and future pandemics.

Read all the details in the Grant Investments & Impacts by area of action section below.

This work is making a difference, not just in individual lives, but across the entire health care system. Québec's health care system recently rose from 7th to 1st in Canada for overall health care performance, a reflection of the investments in innovation and leadership that the MUHC Foundation is proud to support.

"Québec's healthcare system moved from 7th to 1st in Canada for overall healthcare performance, a result of significant investments in innovation and healthcare leadership that are driving meaningful improvements in patient care and system efficiency." — C.D. Howe Institute

The impact of this work is felt every day, in the hospital, where dedicated care teams improve patient outcomes, and in the laboratories, where donor-funded research is setting a new standard. Together, we are not only improving lives but shaping the future of health care.

We are proud to be accredited by the Imagine Canada Standards Program, a national 'trustmark' that signifies our commitment to operational excellence. To achieve this, MUHC Foundation has met 73 rigorous standards across five key areas: board governance, financial accountability and transparency, fundraising practices, staff management, and volunteer involvement. This independent peer review validates that we operate with the highest level of integrity, providing our donors with the confidence that their contributions are managed responsibly and effectively.  

We are proud to be accredited by the Imagine Canada Standards Program.

Grant Investments & Impacts by area of action

Fiscal years 2024 and 2025

  • Total Disbursed – 2023
    $25.8M
    100 Projects
  • Total disbursed — 2024
    $25.4M
    109 projects
  • Total disbursed — 2025
    $34.5M
    150 projects
  • Year-over-year growth
    +35.6%
    +41 projects (+37.6%)


Research

54.8% of total


2023: $17.34M (31 projects)
2024: $14.60M (37 projects)
2025: $18.90M (66 projects)
Growth: +29.5%

Highlighted Projects

DOvEEgene – groundbreaking screening test for ovarian cancer

  • In early 2020, the MUHC Foundation, alongside Genome Canada and Genome Quebec, secured a $6.24 million Genomic Applications Partnership Program (GAPP) grant to advance the DOvEEgene test through final clinical trials. In early 2024, DOvEEgene entered its final phase of clinical trials, following earlier phases that demonstrated the test could detect ovarian and endometrial cancers as early as Stage I, compared to Stage III or IV with conventional diagnostics. The groundbreaking genomic Pap test enrolled more than 5,000 women, followed participants for over two years, identified more than 85 cancers, and demonstrated approximately 70% accuracy in early detection, representing a major advancement in women’s health and precision medicine at the MUHC. https://doveegene.com/about/

Rare genetic illness research initiatives—the SDR Project

  • The SDR Project (DNA and RNA Sequencing for Rare Disease Diagnosis), launched in 2021, advanced precision medicine for patients living with rare and undiagnosed genetic diseases. Created by Shawnea and the Roberts-Hindley family, the initiative aimed to raise $3.1 million, including $1.8 million for specialized equipment to support Dr. Donald Vinh’s research at the MUHC. To date, $2.26 million has been raised. Thanks to philanthropic support, Dr. Vinh’s team identified at least six patients with a newly recognized syndrome and solved complex genetic cases, including a patient misdiagnosed with lymphoma for years, with findings accepted for publication in the British Journal of Haematology, and a young woman suffering from severe infections, with results accepted in Clinical Infection in Practice, the official journal of the British Infection Association. The team also identified the genetic cause of recurrent lymphoma in a patient after more than a decade without answers, advancing personalized care and treatment pathways. https://muhcfoundation.com/works/the-sdr-project-understanding-genetic-diseases

Montréal Sans Hep-C

  • Launched in 2019, Montréal sans HépC is an ongoing community-based initiative working to make Montreal the first city in North America to eliminate hepatitis C. Led by Dr. Marina Klein and partners across Montreal’s leading hospitals, the program addresses a disease affecting more than 58 million people worldwide and over 200,000 Canadians. Although hepatitis C is curable in more than 95% of cases with just 8 to 12 weeks of treatment, stigma and barriers to care continue to leave many untreated. Supported by the MUHC Foundation and major philanthropic partners, including a $1.35 million gift from Scotiabank, the initiative works with 16 community organizations to improve testing, diagnosis, and access to care for underserved populations across Montreal. https://muhcfoundation.com/stories/ambitious-program-aims-to-eliminate-hepatitis-c-in-montreal

Respiratory research initiatives, including the Living Lab

  • Launched in 2021, the Living Lab at the Montreal Chest Institute (MCI) is redefining respiratory medicine by integrating research directly into patient care. Supported by the MUHC Foundation through its $10 million Breathe Easier campaign, the initiative combines wearable technologies, AI-driven analytics, liquid biopsies, and lung regeneration research to move from reactive to predictive care. Patients use smart rings, wristbands, and biosensors that continuously monitor breathing, sleep, oxygen levels, and early signs of deterioration from home, helping clinicians intervene earlier and prevent hospitalizations before symptoms spiral. With chronic lung disease affecting more than 3 million Canadians and only approximately 7,000 lung transplants performed worldwide each year, the Living Lab is accelerating personalized care, earlier interventions, expanded access to clinical trials, and better long-term outcomes for patients. The Montreal Chest Institute sees over 30,000 patients a year, from people suffering common respiratory conditions such as asthma and COPD, all the way to more acute infections such as pneumonia and tuberculosis (TB). https://muhcfoundation.com/news/shining-a-spotlight-on-the-montreal-chest-institute

EndoCARES expansion – supporting endometriosis care for more than 800 patients

  • The MUHC Foundation began supporting EndoCARES (Endometriosis Centre for the Advancement of REsearch and Surgery) in 2022, helping establish Quebec’s first multidisciplinary referral centre dedicated to endometriosis at the MUHC. Affecting approximately 1 in 10 women, endometriosis often took an average of 7 to 10 years to diagnose, leading to chronic pain, infertility, and reduced quality of life. Co-directed by Dr. Dong Bach Nguyen and Dr. Andrew Zakhari, EndoCARES brought together specialists across gynecology, fertility, radiology, colorectal surgery, urology, and thoracic surgery to provide advanced, personalized care. In 2023, the centre supported 171 patients with complex or multi-organ endometriosis, booked 97 patients for complex surgery, and carried 109 referrals into 2024. Between January – April 2024, 76 new patients were seen and 45 patients consented to surgery, expanding access to care across Quebec. EndoCARES expansion is now supporting endometriosis care for more than 800 patients. https://muhcfoundation.com/stories/the-muhc-foundation-is-breaking-the-silence-on-endometriosis , https://healthenews.mcgill.ca/muhc-opens-quebecs-first-multidisciplinary-referral-centre-for-endometriosis/

Courtois Cardiovascular Signature Program – improving heart health outcomes for more than 4,000 patients

  • The MUHC Foundation began supporting the Courtois Cardiovascular Signature Program in 2019, helping launch a groundbreaking precision medicine initiative aimed at better understanding, preventing, and treating heart disease, the cause of approximately 70,000 deaths in Canada each year. The ongoing program has raised more than $17.3 million, surpassing its original $10 million goal. Led by Dr. Matthias Friedrich and Dr. Nadia Giannetti, the 10-year study is following 4,000 participants between the ages of 35 and 79, combining genomic, microbiomic, imaging, lifestyle, and wearable device data to define what makes a healthy heart and identify early markers of cardiovascular disease before symptoms appear. The program has already established one of Canada’s most advanced precision cardiology research platforms, including a fully recruited patient cohort, an integrated cardiovascular biobank, a large-scale imaging and genomics database, and a digital health ecosystem designed to support future AI-driven discoveries. https://muhcfoundation.com/works/reducing-heart-disease-in-canada

AI-based chest X-ray analysis – improving diagnostic speed and accuracy

  • The MUHC Foundation began supporting this AI and Precision Health initiative in 2023, helping advance the use of artificial intelligence to improve access to urgent medical care in Quebec’s remote communities. Led by Dr. Reza Forghani and Dr. Caroline Reinhold, the ongoing project used AI to rapidly analyze X-rays and CT scans, helping physicians identify life-threatening conditions such as strokes, internal bleeding, and collapsed lungs faster. Supported by the MUHC Foundation and a $1 million investment from TD Bank Group, the initiative impacted more than 200,000 people living in Northern Quebec. MUHC radiologists analyzed more than 190,000 X-rays and 100,000 CT scans annually, while patients suffering strokes in rural communities were approximately 30% more likely to die than those in urban centres. https://muhcfoundation.com/stories/artificial-intelligence-helps-save-lives-in-quebecs-remote-communities

Research continues to be the Foundation’s largest area of investment, driving groundbreaking discoveries that will shape the future of health care.

These projects establish the MUHC Research Institute as a leader in advancing precision medicine and addressing some of the most complex health challenges. https://www.researchinfosource.com/top-40-research-hospitals/2025

In addition to these major initiatives, the Foundation supports a wide range of investigator-led studies, early-stage discoveries, and interdisciplinary collaborations through bridge and complementary funding for top researchers, as well as the Precision Oncology Seed Funding Competition. Together, these investments support 66 projects and ensure a strong pipeline, accelerating the translation of research into real-world patient impact.

Patient Care

22.6% of total


2023: $3.61M (62 project)
2024: $5.80M (63 projects)
2025: $7.81M (76 projects)
Growth: +34.6%

Highlighted Projects

Centre for Cardiovascular Disease Prevention

  • The MUHC Foundation supported the Centre for Cardiovascular Disease Prevention, one of the MUHC’s leading prevention-focused cardiology programs dedicated to reducing the risk of heart disease before major cardiac events occur. With heart disease causing approximately 70,000 deaths annually in Canada and affecting 1 in 12 Canadians over the age of 20, the ongoing initiative has advanced early cardiovascular screening, genomic and family-based testing, women’s heart health, and personalized prevention strategies for patients at elevated risk. Founded by Dr. George Thanassoulis, the Family Heart Centre has specialized in inherited cardiovascular conditions, while the CPC’s Exercise Prescription Program has helped patients safely integrate physical activity into long-term heart health prevention.. https://muhc.ca/cpc

RBC Simulation Centre – a donor-supported, advanced medical simulation facility for clinical training

  • Since 2020, the MUHC Foundation has supported the expansion of advanced simulation-based training through the MUHC-i-SIM program, helping prepare the next generation of health care professionals in realistic, high-pressure clinical environments. Supported in part by a $2 million RBC Future Launch gift in 2022, the initiative now helps train more than 5,000 health care professionals annually, including approximately 2,000 new employees each year, 75% of whom are recent graduates. Using high-fidelity operating rooms, ICU simulations, and virtual training technologies, the program strengthens emergency response, teamwork, wellness, and patient safety while reducing medical errors and improving preparedness across the MUHC. https://muhcfoundation.com/works/training-our-health-care-teams

Women’s Healthy Heart Clinic

Art & Heritage – bringing the healing power of art to patients and care environments

  • The MUHC Foundation began supporting the MUHC Art and Heritage Centre in 2008 following the integration of the founding hospital collections into a unified program. Today, the centre preserves and showcases one of Canada’s most significant hospital art and medical heritage collections, featuring more than 6,000 artifacts and works of art spanning over 200 years of medical history. Funding continues today, integrated throughout the MUHC network, the program brings art into clinical and public spaces to create more calming, human-centered care environments. Research associated with the initiative has shown that art can help reduce stress, anxiety, restless behaviour, and noise levels, while improving emotional well-being, comfort, and social connection for patients, families, and care teams. https://muhcfoundation.com/works/the-healing-power-of-art , https://muhc.ca/sites/default/files/micro/m-muhc-heritage/Art%20Heritage%20Fundraising%20brochure%20EN.pdf

Blue Zone – reducing health care emissions and supporting more sustainable operations

  • In 2024, the MUHC became the first institution in Quebec’s health and social services network to adopt a decarbonization roadmap for its buildings, positioning itself as a leader in sustainable health care. With the health care sector responsible for approximately 3.6% of global greenhouse gas emissions, the ongoing initiative aims to achieve carbon neutrality across the MUHC by 2040. Supported by the MUHC Foundation and partners including the City of Montreal and Dunsky Énergie + Climat, the roadmap focused on reducing emissions through electrification, energy efficiency, and modernization projects. Preliminary analyses projected a 25% reduction in energy consumption once measures were fully implemented, while more than 75% of identified greenhouse gas reductions could be achieved at no additional operational cost to the MUHC. https://muhc.ca/news-and-patient-stories/news/first-quebecs-health-and-social-services-network-muhc-adopts-roadmap

Social Services Support

  • The MUHC Foundation began expanding support for patient wellness and social support initiatives in 2020 to help address the growing needs of patients beyond medical care alone. These ongoing programs provided assistance with housing, food security, transportation, mental health, and psychosocial support for vulnerable patients and families. Demand continued to rise as more patients faced financial and social barriers directly impacting health outcomes and recovery. Through interdisciplinary care teams, social workers, and community partnerships, the MUHC helped ensure patients received holistic, compassionate support throughout their treatment journey. In 2025 alone, a targeted MUHC Foundation social support initiative directly assisted 27 vulnerable families through emergency food, clothing, and essential supplies. These initiatives reflected a growing recognition across health care that social determinants such as income, housing, and isolation played a critical role in long-term health and well-being. https://montreal.citynews.ca/2025/12/22/muhc-initiative-growing-patient-needs-beyond-medical-care/

At the MUHC Foundation, we support the programs, care teams, and technologies that improve outcomes and enhance the patient experience across the MUHC. Investments in this area continue to grow, supporting initiatives focused on prevention, and personalized care, including the Artificial Intelligence Monitoring System (AIMS), which enhances patient monitoring and clinical decision-making, simulation-based training programs, women’s health initiatives, and heart disease prevention efforts.

The MUHC’s Artificially Intelligent Monitoring System (AIMS) is using artificial intelligence to help reduce hospital-acquired infections by improving hand hygiene compliance among health care workers. Supported by the MUHC Foundation, the system provides real-time alerts and monitoring to encourage proper handwashing practices — the World Health Organization’s most effective measure for preventing infections. Hospital-acquired infections remain a major challenge in health care, with hand hygiene compliance rates in some hospitals ranging from only 40% to 80%. Studies show that proper hand hygiene can reduce certain nosocomial infections by up to 50%.

Funding also supports physician wellness and development programs, social services that provide assistance beyond clinical care for patients and families, and volunteer services that enhance the patient experience through wayfinding, activity carts, peer support, and in-treatment and evening visits. Together, these initiatives help ensure care extends beyond treatment to address the full spectrum of patient needs.

Hospital Redevelopment

12.9% of total


Capital improvements and specialized equipment at the Glen site

2023: $4.44M (1 project)
2024: $4.44M (1 project)
2025: $4.44M (1 project)
Growth: 0% — stable

The construction of the MUHC’s Glen site, completed in 2015, was one of the largest health care infrastructure projects in Canadian history and among Quebec’s first major public-private partnership (PPP) hospital developments. The $1.3-billion super hospital consolidated the Royal Victoria Hospital, Montreal Children’s Hospital, Montreal Chest Institute, and the Research Institute of the MUHC into a single integrated academic health campus. The site includes approximately 500 single-patient rooms, nearly 20 operating rooms, and advanced research and teaching facilities.

While the Government of Quebec funded the core construction project, philanthropic support from the MUHC Foundation, alongside many other foundations and generous donors and partners, helped fund specialized medical equipment, research facilities, and patient-centred spaces essential to delivering world-class care. Since 2015, ongoing philanthropic investments have continued to support enhancements and strategic upgrades across the Glen site, helping equip the hospital with evolving technologies, advanced tools, and modernized care environments that keep pace with the growing needs of patients and clinical teams. This payment represents the MUHC Foundation’s final installment toward its original commitment to support the development of the Glen site and its future growth.



Equipment, Medical & Lab Supplies
9.7% of total

2023: $0.40M (6 project)
2024: $0.59M (8 projects)
2025: $3.34M (7 projects)
Growth: +463%

Highlighted Projects

Electrophysiology Centre of Excellence - EP Lab

  • Officially opened in November 2024, the MUHC’s Electrophysiology (EP) Centre of Excellence is advancing care for patients with complex heart rhythm disorders through new technology and minimally invasive procedures. The EP Centre serves patients across Quebec while contributing to research in cardiac care. Heart disease remains the second leading cause of death in Canada, responsible for approximately one in every five deaths. Led by Dr. Vidal Essebag and his team, the MUHC recently performed a world-first cardiac electrophysiology procedure using next-generation mapping technology to improve precision and reduce procedure times, helping improve outcomes, reduce recovery times, and expand access to life-saving treatments for patients living with arrhythmias and heart rhythm disorders.https://muhcfoundation.com/works/an-electrophysiology-centre-of-excellence , https://muhc.ca/news-and-patient-stories/news/muhc-advances-care-heart-rhythm-disorders

Gastrointestinal (GI) Therapeutic Endoscopy Room

MUHC Core Molecular Diagnostic Laboratory

  • The Core Molecular Diagnostic Laboratory (CMDL) at the MUHC’s Glen Site advances precision medicine through specialized DNA and RNA testing for cancer and genetic diseases. Operating within the Research Institute of the MUHC and supported by the MUHC Foundation, the laboratory helps clinicians diagnose, monitor, and personalize treatments for complex conditions, including sarcomas, lymphoid neoplasms, and other cancers driven by genetic mutations. These minimally invasive tests can provide real-time cancer monitoring, reduce the need for surgical biopsies, and support more personalized cancer care.

ICU Simulation Equipment - SimMan 3G Plus mannequin.

  • In 2024 the MUHC Foundation funded the acquisition of a SimMan 3G PLUS, an advanced high-fidelity patient simulator used to train health care professionals in realistic emergency and critical care scenarios. The simulator can reproduce a wide range of medical conditions, physiological responses, and drug reactions, allowing teams to safely practice complex procedures, communication, and rapid decision-making before treating real patients. SimMan 3G PLUS supports training in more than 150 clinical skills and can simulate responses to over 145 medications. At the MUHC, this technology strengthens team-based training across emergency medicine, intensive care, trauma, and resuscitation, helping improve patient safety, reduce medical errors, and enhance readiness for high-risk situations.

Significant growth in this category reflects increased investment in essential clinical and diagnostic infrastructure. Key projects include the Electrophysiology Lab, advancing the treatment of cardiac arrhythmias; the GI Endoscopy Suite, supporting the diagnosis and treatment of gastric and hepatopancreatobiliary (HPB) cancers as well as benign gastrointestinal conditions; and the Core Molecular Diagnostic Laboratory, equipped with advanced genetic sequencing technology. Investments also include ICU simulation equipment, strengthening clinical training and preparedness.

Together, these initiatives improve the precision, efficiency, and safety of care delivery across the MUHC. Beyond these major projects, funding in this category supports a wide range of equipment needs across departments—from diagnostic tools to specialized laboratory technologies—ensuring clinical teams have access to the resources they need to deliver timely, high-quality care.

Citations:

The McGill University Health Centre (MUHC) is an academic health network, and one of the largest and most modern in North America

https://montreal.citynews.ca/2...

Attracting, training and retaining top talent is at the heart of Quebec’s scientific strategy.” — Rémi Quirion, Chief Scientist of Quebec, speaking about the RI-MUHC fellowship initiative.

https://muhc.ca/muhc-glance

https://rimuhc.ca/about-us

https://rimuhc.ca/the-ri-muhc-...

https://rimuhc.ca/-/canada-s-t...

**The Research Institute of the McGill University Health Centre (RI-MUHC) is the leading research hospital in Quebec, ranking #1 in the province and #3 in Canada according to Research Infosource (2024).

**https://researchinfosource.com...

https://muhc.ca/muhc-media

https://www.lapresse.ca/actual...

https://www.montrealgazette.co...

https://themontrealeronline.co...

https://globalnews.ca/video/11...

https://globalnews.ca/video/11...

https://themontrealeronline.co...

The MUHC and its network

The MUHC is one of the largest bilingual university networks in North America. They act as a referral center for third- and fourth-line care (specialized care like oncology, cardiology, surgery, rare diseases and transplant) for a population catchment representing 1.9 million Quebecers and 63% of Quebec's territory.

Ever year:

  • They receive over 515,000 outpatient visits, including 177,000 emergency room visits
  • They perform over 30,000 operations
  • Deliver more than 3,000 babies

Their team includes:

  • 10,000 nurses and employees
  • 2,000 residents and students in health sciences
  • 1,000 graduate and post-doctoral students
  • 1,700 research employees
  • 1,500 volunteers
  • 1,356 doctors, dentists and pharmacists

The MUHC is also the largest research hospital in Quebec and the third largest in Canada, surpassed only by its Ontario partners University Health Network (UHN) and SickKids.

For Quebec, the MUHC therefore represents a major gateway for innovations in patient care such as clinical studies that can save lives.

The inauguration of the new Glen site of the MUHC in 2015 has forever brought research and care closer together. The Research Institute of the MUHC is now under the same roof as its hospital. With its clinical research unit and the creation of open-concept research space as well as shared research equipment, medical research is exponentially accelerating.

Physically and intellectually, the distance between patient bedside and research is greatly reduced. The doctor treating patients this morning will study their disease in the laboratory this afternoon. That is the power of a research hospital like the MUHC.